Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling.

Alphonse, Noémie; Wanford, Joseph J; Voak, Andrew A; Gay, Jack; Venkhaya, Shayla; Burroughs, Owen; Mathew, Sanjana; Lee, Truelian; Evans, Sasha L; Zhao, Weiting; Frowde, Kyle; Alrehaili, Abrar; Dickenson, Ruth E; Munk, Mads; Panina, Svetlana; Mahmood, Ishraque F; Llorian, Miriam; Stanifer, Megan L; Boulant, Steeve; Berchtold, Martin W; Bergeron, Julien R C; Wack, Andreas; Lesser, Cammie F; Odendall, Charlotte.

Cell ; 185(13): 2354-2369.e17, 2022 06 23.

Artigo em Inglês | MEDLINE | ID: mdl-35568036

2.

The interferon landscape along the respiratory tract impacts the severity of COVID-19.

Sposito, Benedetta; Broggi, Achille; Pandolfi, Laura; Crotta, Stefania; Clementi, Nicola; Ferrarese, Roberto; Sisti, Sofia; Criscuolo, Elena; Spreafico, Roberto; Long, Jaclyn M; Ambrosi, Alessandro; Liu, Enju; Frangipane, Vanessa; Saracino, Laura; Bozzini, Sara; Marongiu, Laura; Facchini, Fabio A; Bottazzi, Andrea; Fossali, Tommaso; Colombo, Riccardo; Clementi, Massimo; Tagliabue, Elena; Chou, Janet; Pontiroli, Antonio E; Meloni, Federica; Wack, Andreas; Mancini, Nicasio; Zanoni, Ivan.

Cell ; 184(19): 4953-4968.e16, 2021 09 16.

Artigo em Inglês | MEDLINE | ID: mdl-34492226

3.

Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection.

Aegerter, Helena; Kulikauskaite, Justina; Crotta, Stefania; Patel, Harshil; Kelly, Gavin; Hessel, Edith M; Mack, Matthias; Beinke, Soren; Wack, Andreas.

Nat Immunol ; 21(2): 145-157, 2020 02.

Artigo em Inglês | MEDLINE | ID: mdl-31932810

4.

The role of recruitment versus training in influenza-induced lasting changes to alveolar macrophage function.

Iliakis, Chrysante S; Kulikauskaite, Justina; Aegerter, Helena; Li, Fengqi; Piattini, Federica; Jakubzick, Claudia V; Guilliams, Martin; Kopf, Manfred; Wack, Andreas.

Nat Immunol ; 24(10): 1639-1641, 2023 10.

Artigo em Inglês | MEDLINE | ID: mdl-37640788

5.

A serpin shapes the extracellular environment to prevent influenza A virus maturation.

Dittmann, Meike; Hoffmann, Hans-Heinrich; Scull, Margaret A; Gilmore, Rachel H; Bell, Kierstin L; Ciancanelli, Michael; Wilson, Sam J; Crotta, Stefania; Yu, Yingpu; Flatley, Brenna; Xiao, Jing W; Casanova, Jean-Laurent; Wack, Andreas; Bieniasz, Paul D; Rice, Charles M.

Cell ; 160(4): 631-643, 2015 Feb 12.

Artigo em Inglês | MEDLINE | ID: mdl-25679759

6.

Endothelial AHR activity prevents lung barrier disruption in viral infection.

Major, Jack; Crotta, Stefania; Finsterbusch, Katja; Chakravarty, Probir; Shah, Kathleen; Frederico, Bruno; D'Antuono, Rocco; Green, Mary; Meader, Lucy; Suarez-Bonnet, Alejandro; Priestnall, Simon; Stockinger, Brigitta; Wack, Andreas.

Nature ; 621(7980): 813-820, 2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-37587341

7.

Guarding the frontiers: the biology of type III interferons.

Wack, Andreas; Terczynska-Dyla, Ewa; Hartmann, Rune.

Nat Immunol ; 16(8): 802-9, 2015 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-26194286

8.

Monocytes work harder under pressure.

Tolar, Pavel; Wack, Andreas.

Nat Immunol ; 20(11): 1422-1424, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31595058

9.

The FAM13A Long Isoform Regulates Cilia Movement and Co-ordination in Airway Mucociliary Transport.

Howes, Ashleigh; Rogerson, Clare; Belyaev, Nikolai; Karagyozova, Tina; Rapiteanu, Radu; Fradique, Ricardo; Pellicciotta, Nicola; Mayhew, David; Hurd, Catherine; Crotta, Stefania; Singh, Tanya; Dingwell, Kevin; Myatt, Anniek; Arad, Navot; Hasan, Hikmatyar; Bijlsma, Hielke; Panjwani, Aliza; Vijayan, Vinaya; Young, George; Bridges, Angela; Petit-Frere, Sebastien; Betts, Joanna; Larminie, Chris; Smith, James C; Hessel, Edith M; Michalovich, David; Walport, Louise; Cicuta, Pietro; Powell, Andrew J; Beinke, Soren; Wack, Andreas.

Am J Respir Cell Mol Biol ; 2024 May 01.

Artigo em Inglês | MEDLINE | ID: mdl-38691660

10.

Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model.

Wing, Peter A C; Prange-Barczynska, Maria; Cross, Amy; Crotta, Stefania; Orbegozo Rubio, Claudia; Cheng, Xiaotong; Harris, James M; Zhuang, Xiaodong; Johnson, Rachel L; Ryan, Kathryn A; Hall, Yper; Carroll, Miles W; Issa, Fadi; Balfe, Peter; Wack, Andreas; Bishop, Tammie; Salguero, Francisco J; McKeating, Jane A.

PLoS Pathog ; 18(9): e1010807, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-36067210

11.

Teaching Old Dogs New Tricks? The Plasticity of Lung Alveolar Macrophage Subsets.

Kulikauskaite, Justina; Wack, Andreas.

Trends Immunol ; 41(10): 864-877, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32896485

12.

Stop the executioners.

Wack, Andreas.

Nat Immunol ; 16(1): 6-8, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25521671

13.

Multiple Levels of Control Determine How E4bp4/Nfil3 Regulates NK Cell Development.

Kostrzewski, Tomasz; Borg, Aaron J; Meng, Yiran; Filipovic, Iva; Male, Victoria; Wack, Andreas; DiMaggio, Peter A; Brady, Hugh J M.

J Immunol ; 200(4): 1370-1381, 2018 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-29311361

14.

TRAIL+ monocytes and monocyte-related cells cause lung damage and thereby increase susceptibility to influenza-Streptococcus pneumoniae coinfection.

Ellis, Gregory T; Davidson, Sophia; Crotta, Stefania; Branzk, Nora; Papayannopoulos, Venizelos; Wack, Andreas.

EMBO Rep ; 16(9): 1203-18, 2015 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-26265006

15.

Themis2 is not required for B cell development, activation, and antibody responses.

Hartweger, Harald; Schweighoffer, Edina; Davidson, Sophia; Peirce, Matthew J; Wack, Andreas; Tybulewicz, Victor L J.

J Immunol ; 193(2): 700-7, 2014 Jul 15.

Artigo em Inglês | MEDLINE | ID: mdl-24907343

16.

The transcription factor E4BP4 is not required for extramedullary pathways of NK cell development.

Crotta, Stefania; Gkioka, Annita; Male, Victoria; Duarte, João H; Davidson, Sophia; Nisoli, Ilaria; Brady, Hugh J M; Wack, Andreas.

J Immunol ; 192(6): 2677-88, 2014 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-24534532

17.

Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia.

Crotta, Stefania; Davidson, Sophia; Mahlakoiv, Tanel; Desmet, Christophe J; Buckwalter, Matthew R; Albert, Matthew L; Staeheli, Peter; Wack, Andreas.

PLoS Pathog ; 9(11): e1003773, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-24278020

18.

Influenza A virus impairs control of Mycobacterium tuberculosis coinfection through a type I interferon receptor-dependent pathway.

Redford, Paul S; Mayer-Barber, Katrin D; McNab, Finlay W; Stavropoulos, Evangelos; Wack, Andreas; Sher, Alan; O'Garra, Anne.

J Infect Dis ; 209(2): 270-4, 2014 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-23935205

19.

Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88.

Seubert, Anja; Calabro, Samuele; Santini, Laura; Galli, Barbara; Genovese, Alessia; Valentini, Sara; Aprea, Susanna; Colaprico, Annalisa; D'Oro, Ugo; Giuliani, Marzia M; Pallaoro, Michele; Pizza, Mariagrazia; O'Hagan, Derek T; Wack, Andreas; Rappuoli, Rino; De Gregorio, Ennio.

Proc Natl Acad Sci U S A ; 108(27): 11169-74, 2011 Jul 05.

Artigo em Inglês | MEDLINE | ID: mdl-21690334

20.

Regulation of BCR-mediated Ca²⁺ mobilization by MIZ1-TMBIM4 safeguards IgG1⁺ GC B cell-positive selection.

Zhang, Lingling; Toboso-Navasa, Amparo; Gunawan, Arief; Camara, Abdouramane; Nakagawa, Rinako; Finsterbusch, Katja; Chakravarty, Probir; Newman, Rebecca; Zhang, Yang; Eilers, Martin; Wack, Andreas; Tolar, Pavel; Toellner, Kai-Michael; Calado, Dinis Pedro.

Sci Immunol ; 9(94): eadk0092, 2024 Apr 05.

Artigo em Inglês | MEDLINE | ID: mdl-38579014

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